POWER, METALLURGICAL AND CHEMICAL MECHANICAL ENGINEERING CRYOGENIC INSTRUMENT REFRIGERATING BY LIQUID NITROGEN IN UNDERHEATED CONDUCTION
https://doi.org/10.21822/2073-6185-2019-46-1-19-31
Abstract
Objectives. Cryogenic surgical instruments have been successfully used to conduct tumor ablation. For a long time, cryoablation procedures in Russia were carried out using cryodestructors cooled with liquid nitrogen, which are able to remove heat from the ablation object with high heat flux density and quickly form a cryoablation zone, while being relatively cheap and easy to operate. However, these instruments turned out to be unsuitable for minimally invasive surgeries; therefore, they are squeezed out of practical medicine and cryosurgical instruments are cooled by throttling argon gas. This led to the purpose of the study - the choice of equipment for the organization of local supercooling of pathological tissue.
Method. To solve the problem of optimizing the cryogenic pipeline, a method was chosen for finding the Pareto-optimal solution. To solve this problem, it is sufficient to increase the pressure in the fluid flow directed to the NCS using a liquid micropump. In the role of quality criteria in this task, we selected: hydraulic loss power and heat loss power.
Result. The following results were obtained: the minimum pressure in the vessel, which ensures the movement of the fluid in a single-phase state, according to the magi-line of 1 m length is 0.75 MPa; With this pressure, through a line with a diameter of 1 mm, the flow rate is maintained up to 6 kg / h; heat dissipation ability of the instrument reaches 608 watts. The thermal load on the cooling system of the heatdissipating device of the device for CA is unsteady and is formed due to the heat reserve accumulated in the patient's tissues.
Conclusion. The use of liquid nitrogen in the undersized cryosurgical equipment makes it possible to overcome the noted drawbacks of liquid cryodestructors.
About the Authors
A. V. GlushaevRussian Federation
Graduate student, Faculty of Cryogenic Engineering.
9 Lomonosov Str., St. Petersburg 9190001.
V. N. Zamarashkina
Russian Federation
Cand. Sci. (Technical), Assoc. Prof., Tutor at the Faculty of Cryogenic Engineering.
9 Lomonosov Str., St. Petersburg 9190001.
T. A. Malysheva
Russian Federation
Cand. Sci. (Technical), Assoc. Prof., Assoc. Prof. at the Faculty of Software Engineering and Computer Engineering.
9 Lomonosov Str., St. Petersburg 9190001.E. V. Sokolova
Russian Federation
Senior Lecturer at the Faculty of Cryogenic Engineering.
9 Lomonosov Str., St. Petersburg 9190001.
References
1. Sumida S. Mechanism of tissue injury in cryosurgery. In: 16th World Congress of the ISC. October 29– November 2, 2011; Hofburg, Vienna, Austria. Korpan N.N., Sumida S. (editors). Vienna: University Facultas Publisher; 2011; p. 55–56.
2. Belyayev A.M., Prokhorov G.G. Kriogennyye tekhnologii v onkologii. Voprosy onkologii 2015; 61(3): 317–322. [Belyaev A.M., Prokhorov G.G. Cryogenic technologies in oncology. Voprosy onkologii 2015; 61(3): 317–322. (In Russ.)]
3. Robilotto A.T., Baust J.M., Van Buskirk R.G., Gage A.A., Baust J.G. Temperature-dependent activation of differential apoptotic pathways during cryoablation in a human prostate cancer model. Prostate Cancer Prostatic Dis 2013; 16(1): 41– 49, https://doi.org/10.1038/pcan.2012.48.
4. Xu K., Korpan N.N., Niu L. Modern cryosurgery for cancer. World Scientific Publishing; 2012, https://doi. org/10.1142/8004.
5. Wojciech R. The importance of cryosurgery in gynecological practice. Ginekol Pol 2011; 82(8): 618–622.
6. Govorov A.V., Vasilyev A.O., Pushkar D.U. Specifics of prostate cryoablation. Biomedical Engineering 2015; 49(1): 54–59, https://doi.org/10.1007/s10527-015-9496-8.
7. Berglund R.K., Jones J.S. Cryotherapy for prostate cancer. In: Interventional urology. Rastinehad A.R., Siegel D.N., Pinto P.A., Wood B.J. (editors). Springer International Publishing; 2016; p. 165–171, https://doi.org/10.1007/978-3- 319-23464-9_13.
8. Korpan N.N. Modern cryosurgery: present and future. In: 16th World Congress of the ISC. October 29– November 2, 2011; Hofburg, Vienna, Austria. Korpan N.N., Sumida S. (editors). Vienna: The University Publisher Facultas; 2011; p. 29–30.
9. Butorina A., Arkharov A., Matveev V. Dreams and reality of cryogenic technology in surgery. In: The 12th CRYOGENICS IIR International Conference. September 11–14, 2012; Dresden, Germany. Czech Republic; 2012; p. 467–474.
10. Erinjeri J.P., Clark T.W.I. Cryoablation: mechanism of action and devices. J Vasc Interv Radiol 2010; 21(8): S187– S191, https://doi.org/10.1016/j.jvir.2009.12.403.
11. Shakurov A.V., Pushkarev A.V., Pushkarev V.A., Tsyganov D.I. Predposylki dlya razrabotki novogo pokoleniya kriokhirurgicheskogo oborudovaniya (obzor) // Sovremennyye tekhnologii v meditsine. - 2017. T. 9. № 2. s. 178-189. [Shakurov A.V., Pushkarev A.V., Pushkarev V.A., Tsyganov D.I. Prerequisites for the development of a new generation of cryosurgical equipment (review) // Modern technologies in medicine. - 2017. V. 9. № 2. p. 178-189. (In Russ.)]
12. Kondratenko R.O. Razrabotka i sozdaniye apparatury dlya kriokhirurgii i krioterapii: diss. na soiskaniye uch.stepeni kand.tekhn.nauk po spets. 05.04.03. M.: MGTU im. N.E. Baumana, 2012. – 140 s. [Kondratenko R.O. Development and creation of equipment for cryosurgery and cryotherapy: Diss. for the degree of Cand.Tech.Science on spec. 04/05/03. M .: MSTU. N.E. Bauman, 2012. - 140 p. (In Russ.)]
13. Tsyganov D.I. Kriomeditsina: protsessy i apparaty. Monografiya. - Moskva: SAYNS-PRESS, 2011 - 304 stranitsy. [Tsiganov D.I. Cryomedicine: processes and devices. Monograph. - Moscow: SAINS-PRESS, 2011 - 304 pages. (In Russ.)]
14. Baranov A.YU., Sokolova Ye.V. Novyye tekhnologii snabzheniya kriokhirurgicheskikh instrumentov zhidkim azotom // VIII Mezhdunarodnaya nauchno-tekhnicheskaya konferentsiya «Nizkotemperaturnyye i pishchevyye tekhnologii v XXI veke» (Sankt-Peterburg, 15-17 noyabrya 2017 g.): Materialy konferentsii - 2017. - c. 112-114 [Baranov A.Yu., Sokolova E.V. New technologies for supplying cryosurgical instruments with liquid nitrogen // VIII International Scientific and Technical Conference "Low-temperature and food technologies in the XXI century" (St. Petersburg, November 15-17, 2017): Conference materials - 2017. - c. 112-114(In Russ.)]
15. Sokolova Ye.V. Ispol'zovaniye nedogretoy kriogennoy zhidkosti dlya otvoda teploty ot ob"yekta kriokhirurgicheskogo vozdeystviya // Krioterapiya v Rossii: materialy X Mezhdunarodnoy nauchnoprakticheskoy konferentsii (Sankt-Peterburg, 18 maya 2017 g.) - 2018. - s. 83-88. [Sokolova E.V. The use of underheated cryogenic liquid for removal of heat from the object of cryosurgical effects // Cryotherapy in Russia: materials of the X International Scientific Practical Conference (St. Petersburg, May 18, 2017) - 2018. - p. 83-88. (In Russ.)]
16. Zaytsev A.V., Logvinenko Ye.V. Raschet techeniya vyazkoy zhidkosti v kanale s uchetom izmeneniya fazovogo sostoyaniya // Vestnik Sankt-Peterburgskogo universiteta. Seriya 1. Matematika. Mekhanika. Ast-ronomiya - 2012. - № 4. - s. 87-91 [Zaitsev A.V., Logvinenko E.V. Calculation of the flow of a viscous fluid in the channel taking into account changes in the phase state // Bulletin of St. Petersburg University. Series 1. Mathematics. Mechanics. Astronomy - 2012. - № 4. - p. 87-91(In Russ.)]
17. Akulov L.A., Borzenko Ye.I., Zaytsev A.V. Teplofizicheskiye svoystva i fazovoye ravnovesiye kriogennykh produktov: spravochnik-Sankt-Peterburg: Gosudarstvennyy universitet nizkikh temperatur i pishchevykh tekhnologiy, 2009- 567 s [Akulov L.A., Borzenko E.I., Zaitsev A.V. Thermophysical properties and phase equilibrium of cryogenic products: Handbook, St. Petersburg: State University of Low Temperatures and Food Technologies, 2009- 567 p. (In Russ.)]
18. Bankoff S.G. A variable density single-fluid model for two-phase flow with particular reference to steamwater flow// J. Heat Transfer. 1960. Vol.82, p.265-272
19. Kozlov B.K. Rezhimy i formy dvizheniya vozdukhovodyanoy smesi v vertikal'noy trube. Sb. «Gidrodinamika i teploobmen v kotlakh vysokogo davleniya». Izd.AN SSSR, 1955 [Kozlov B.K. Modes and forms of movement of the air-water mixture in a vertical pipe. Sat "Hydrodynamics and heat transfer in high-pressure boilers." Ed.AN USSR, 1955. (In Russ.)]
20. Kostyuk V.V. Metody rascheta protsessov zapolneniya i okhlazhdeniya yemkostey i magistraley kriogennymi zhidkostyami.- Novosibirsk: Akademiya nauk SSSR Sibirskoye otdeleniye Institut teplofizi-ki,1990 [Kostyuk V.V. Methods for calculating the processes of filling and cooling of tanks and highways with cryogenic liquids.- Novosibirsk: USSR Academy of Sciences Siberian Branch of the Institute of Thermal Physics, 1990(In Russ.)]
21. Labuntsov D.A. Fizicheskiye osnovy energetiki. Izbrannyye trudy po teploobmenu, gidrodinamike, termodinamike. M.: Izd-vo MEI, 2000 [Labuntsov D.A. Physical basis of energy. Selected works on heat transfer, fluid dynamics, thermodynamics. M .: MEI, 2000 (In Russ.)]
22. Chiskholm D. Dvukhfaznyye techeniya v truboprovodakh i teploobmennikakh: Per. s ang./ Velikobritaniya.– M.:Nedra,1986.–204 s. [Chisholm D. Two-phase flow in pipelines and heat exchangers: Trans. from English / United Kingdom. –M .: Nedra, 1986. – 204 p. (In Russ.)]
23. Zaytsev A.V., Logvinenko Ye.V. Optimizatsiya kriogennogo truboprovoda // Omskiy nauchnyy vestnik - 2014. - № 3 (133). - c. 164-168 [Zaitsev A.V., Logvinenko E.V. Optimization of the cryogenic pipeline // Omsk Scientific Herald - 2014. - № 3 (133). - p. 164-168 (In Russ.)]
24. Zaytsev A.V., Logvinenko Ye.V. Resheniye zadachi optimizatsii kriogennogo truboprovoda metodom poiska Pareto-optimal'nogo resheniya // Vestnik Mezhdunarodnoy akademii kholoda - 2015. № 2. - s. 55-60 [Zaitsev A.V., Logvinenko E.V. Solving the problem of optimizing a cryogenic pipeline using the Pareto optimal solution search // Bulletin of the International Academy of Refrigeration - 2015. No. 2. - p. 55-60 (In Russ.)]
25. Logvinenko Ye.V. Optimizatsiya kriogennogo truboprovoda metodom poiska Pareto-optimal'nogo resheniya // V sbornike: Al'manakh nauchnykh trudov molodykh uchenykh Universiteta ITMO-2015. - s. 110-112. [Logvinenko E.V. Optimization of the cryogenic pipeline using the Pareto-optimal solution search // In collection: Almanac of scientific works of young scientists of ITMO-2015 University. - p. 110-112. (In Russ.)]
26. Sobol' I.M., Statnikov R.B. Vybor optimal'nykh parametrov v zadachakh so mnogimi kriteriyami. – M.: Nauka, 1981. – 111 s. [Sobol I.M., Statnikov R.B. The choice of optimal parameters in problems with many criteria. - M .: Science, 1981. - 111 p. (In Russ.)]
27. Podinovskiy V.V., Nogin V.D. Pareto-optimal'nyye resheniya mnogokriterial'nykh zadach. – M.: Nauka, 1982. [Podinovskiy V.V., Nogin V.D. Pareto optimal solutions for multicriteria problems. - M.: Science, 1982. (In Russ.)]
28. Arkharov A.M., Arkharov I.A., Tychkova S.O. K zadache ob izmenenii temperatury kriogennykh zhidkostey pri otkachke ikh parov i khranenii // Vestnik MGTU im. N.E. Baumana. Ser. Mashinostroyeniye. – 2010. – S. 41–45 [Arkharov A.M., Arkharov I.A., Tychkova S.O. On the problem of changing the temperature of cryogenic liquids when pumping out their vapors and storing // Vestnik MGTU im. N.E. Bauman. Ser. Engineering. - 2010. - P. 41–45(In Russ.)]
29. Ivanov V.I., Yeremeyev V.A. Issledovaniye protsessa polucheniya pereokhlazhdennogo szhizhennogo prirodnogo gaza. Al'manakh nauchnykh rabot molodykh uchenykh Universiteta ITMO. Tom 1. – SPb.: Universitet ITMO, 2017. – 348 s. Ivanov V.I., Yeremeyev V.A. Issledovaniye protsessa polucheniya pereokhlazhdennogo szhizhennogo prirodnogo gaza. Al'manakh nauchnykh rabot molodykh uchenykh Universiteta ITMO. Tom 1. – SPb.: Universitet ITMO, 2017. – 348 s. Ivanov V.I., Eremeev V.A. Study of the process of obtaining supercooled liquefied natural gas. Almanac of scientific works of young scientists of ITMO University. Volume 1. - SPb .: ITMO University, 2017. - 348 p. (In Russ.)]
30. Baranov A.YU., Malysheva T.A., Sidorova A.YU. Modelirovaniye protsessa konvektivnogo okhlazhdeniya tela na komp'yutere: Metod. ukazaniya dlya studentov spets.140401 vsekh form obucheniya. – SPb.: SPbGUNiPT, 2011. – 38 s. [Baranov A.Yu., Malysheva T.A., Sidorova A.Yu. Simulation of the process of convective body cooling on a computer: Method. instructions for students of special. 140401 of all forms of education. - SPb .: SPbGUNIPT, 2011. - 38 p. (In Russ.)]
Review
For citations:
Glushaev A.V., Zamarashkina V.N., Malysheva T.A., Sokolova E.V. POWER, METALLURGICAL AND CHEMICAL MECHANICAL ENGINEERING CRYOGENIC INSTRUMENT REFRIGERATING BY LIQUID NITROGEN IN UNDERHEATED CONDUCTION. Herald of Dagestan State Technical University. Technical Sciences. 2019;46(1):19-31. (In Russ.) https://doi.org/10.21822/2073-6185-2019-46-1-19-31